Association between the prognostic nutritional index and early mortality of AML patients after allogeneic HSCT: a retrospective cohort analysis
The PNI exhibits a L-shaped association with 180-day mortality in AML patients post-HSCT, emerging as a significant predictor with a critical threshold identified at PNI 46. Below this threshold, declining PNI values correlate with increased mortality risk, underscoring its clinical utility in driving nutritional interventions to enhance post-transplant survival outcomes.
Authors
- Yimei Feng
- Linlin Wang (ORCID: https://orcid.org/0000-0002-7014-2149)
- Yali Wang (ORCID: https://orcid.org/0009-0001-9033-5677)
- Feng Ran
- Liquan Jiang (ORCID: https://orcid.org/0000-0002-7203-5953)
- Gangping Li (ORCID: https://orcid.org/0000-0002-6033-6812)
- Xi Zhang
- Xiaoli Chen
- Jie Tang
Institutions
- Army Medical University (CN)
- Xinjiang Medical University (CN)
- Henan Cancer Hospital (CN)
- Second Affiliated Hospital of Xinjiang Medical University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-02-04
- DOI
- https://doi.org/10.3389/fonc.2026.1754463
- Primary Topic
- Inflammatory Biomarkers in Disease Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Army Medical University
- Centre Scientifique et Technique du Bâtiment