Clinical Evidence of Valvelike Structures in Schlemm Canal and Their Anatomic Links Detected by Optical Coherence Tomography
This is the first clinical OCT evidence of valvelike structures in Schlemm canal, which were visualized in all 10 postoperative eyes. Based on structural and dimensional similarities, the authors hypothesize that the 3 in vivo clinical OCT structures closely resemble the SIV, HCF, and CVC. Our preliminary results bridge the gap from the laboratory to the clinic and add support to the addition of these 3 structures to the anatomy of the living human aqueous outflow system.
Authors
- A Liu
- Matthew J. Holliman
- R. D. Fellman
- Xin Chen (ORCID: https://orcid.org/0000-0003-1200-9291)
- Steven Padilla
- Elizabeth Martin
- Davinder Grover
- Ruikang K. Wang
Institutions
- Washington State Department of Health (US)
- University of Washington (US)
- University of Illinois Chicago (US)
- Whitten Laser Eye (US)
- Beijing Anzhen Hospital (CN)
- Glaucoma Associates of Texas (US)
Publication Details
- Journal
- American Journal of Ophthalmology
- Published
- 2026-02-04
- DOI
- https://doi.org/10.1016/j.ajo.2026.01.032
- Primary Topic
- Optical Coherence Tomography Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00