An Update on the Management of Acute Variceal Bleeding: A Narrative Review

Acute variceal bleeding (AVB) is a known complication of decompensated cirrhosis and carries with it a high mortality rate. Understanding the basic underlying pathophysiologic processes that lead to the development of varices and how to prevent progression of this disease is crucial for an intensivist. Once bleeding occurs, intensivists must be able to navigate a complex presentation of impending respiratory failure and hemorrhagic shock. A multidisciplinary approach to AVB including medical therapies combined with procedural interventions such as endoscopy, balloon tamponade, and emergency surgery must all be considered in severe cases. In this narrative review, we aim to provide an updated and comprehensive overview of the prevention and management of variceal bleeding in patients with cirrhosis.

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Publication Details

Journal
Journal of Intensive Care Medicine
Published
2026-02-03
DOI
https://doi.org/10.1177/08850666261417587
Primary Topic
Liver Disease and Transplantation
Type
article
Field-Weighted Citation Impact
0.00
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article

An Update on the Management of Acute Variceal Bleeding: A Narrative Review

Pratik Gandhi, David W Wang, Kate Simeon, Ezeldeen Abuelkasem
Journal of Intensive Care Medicine
Liver Disease and Transplantation
article

An Update on the Management of Acute Variceal Bleeding: A Narrative Review

Pratik Gandhi, David W Wang, Kate Simeon, Ezeldeen Abuelkasem
article en

Abstract

Acute variceal bleeding (AVB) is a known complication of decompensated cirrhosis and carries with it a high mortality rate. Understanding the basic underlying pathophysiologic processes that lead to the development of varices and how to prevent progression of this disease is crucial for an intensivist. Once bleeding occurs, intensivists must be able to navigate a complex presentation of impending respiratory failure and hemorrhagic shock. A multidisciplinary approach to AVB including medical therapies combined with procedural interventions such as endoscopy, balloon tamponade, and emergency surgery must all be considered in severe cases. In this narrative review, we aim to provide an updated and comprehensive overview of the prevention and management of variceal bleeding in patients with cirrhosis.

Journal of Intensive Care Medicine
University of Pittsburgh (US)
Good health and well-being
Openalex Percentile: Top 66%
Liver Disease and Transplantation
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