Theophylline Inhibits Capillary Degeneration in Early Diabetic Retinopathy
Theophylline significantly inhibited the degeneration of retinal capillaries in early DR and can help investigate mechanistic differences in the pathogenesis of retinal capillary degeneration and neural dysfunction in diabetes.
Authors
- Jianying Kiser (ORCID: https://orcid.org/0000-0002-0307-2857)
- Aicha Saadane (ORCID: https://orcid.org/0000-0001-9985-2147)
- Emma M. Lessieur (ORCID: https://orcid.org/0000-0001-9120-0291)
- Jie Tang (ORCID: https://orcid.org/0000-0002-3538-4433)
- Timothy S. Kern (ORCID: https://orcid.org/0000-0003-1188-0739)
- Zak R. Bollinger
- Yunpeng Du
- Chieh A. Lee
- Alice Oum
Institutions
- University of California, Irvine (US)
- Case Western Reserve University (US)
Publication Details
- Journal
- Investigative Ophthalmology & Visual Science
- Published
- 2026-02-03
- DOI
- https://doi.org/10.1167/iovs.67.2.8
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Research to Prevent Blindness
- National Institutes of Health
- University of California, Irvine