Impact of total gastrectomy plus perioperative PD-1 inhibitors on survival in locally advanced gastric cancer

Total gastrectomy combined with perioperative sintilimab +XELOX regimen for LAGC significantly improves radical surgery, pathological response rate and long-term survival, with a manageable safety profile, offering a potentially effective treatment strategy.

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Publication Details

Journal
Frontiers in Oncology
Published
2026-02-03
DOI
https://doi.org/10.3389/fonc.2026.1771329
Primary Topic
Gastric Cancer Management and Outcomes
Type
article
Field-Weighted Citation Impact
0.00
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article

Impact of total gastrectomy plus perioperative PD-1 inhibitors on survival in locally advanced gastric cancer

Min Emma Huang, Fan Zhang
Frontiers in Oncology
Gastric Cancer Management and Outcomes
article

Impact of total gastrectomy plus perioperative PD-1 inhibitors on survival in locally advanced gastric cancer

Min Emma Huang, Fan Zhang
article en

Abstract

Total gastrectomy combined with perioperative sintilimab +XELOX regimen for LAGC significantly improves radical surgery, pathological response rate and long-term survival, with a manageable safety profile, offering a potentially effective treatment strategy.

Frontiers in OncologyVol. 16
Yangtze University (CN)
Good health and well-being
Openalex Percentile: Top 69%
Gastric Cancer Management and Outcomes
DOIOpen Access PDFOpenAlex
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