Case Report: Upper extremity deep vein thrombosis revealing an occult invasive ductal breast carcinoma

Upper extremity deep vein thrombosis is frequently associated with malignancy and may represent its first clinical manifestation, as in our patient, whose axillary breast carcinoma invaded the arteriovenous structures without detectable breast lesions. Early recognition of this condition is essential for timely diagnosis and improved prognosis. Direct oral anticoagulants represent a valuable therapeutic option with multiple advantages. Their potential antineoplastic effects-particularly those of factor XI inhibitors currently under investigation-may provide additional benefits in cancer-associated thrombosis.