Angiography-Derived Physiology for Coronary Artery Disease Assessment: Expert Opinion From a SCAI Roundtable
Angiography-derived physiology (ADP) is an emerging technique that offers streamlined, wire-free assessment of epicardial coronary physiology. This is accomplished by applying computational fluid dynamics or, in some cases, mathematical formulas in conjunction with artificial intelligence to standard coronary angiographic images. This approach represents a potential paradigm shift in the catheterization laboratory workflow. Despite its early promise, obstacles to the adoption and routine use of ADP remain. This document represents expert opinion from a scientific roundtable on ADP for coronary artery assessment sponsored by the Society for Cardiovascular Angiography & Interventions. It provides a comprehensive overview of the underlying concepts of ADP, outlines its optimal clinical application based on current evidence, highlights key advantages and limitations, reviews available software solutions, and discusses future directions.
Authors
- Sanjeev B. Patel
- Amir K. Kaki
- Devraj Sukul (ORCID: https://orcid.org/0000-0003-4709-3390)
- Allen Jeremias
- Mirvat Alasnag
- Nieves Gonzalo
- Doosup Shin
- Karim M. Al-Azizi
- William F. Fearon
- Ziad A. Ali
- Yader Sandoval
- Carlos Collet
- Javier Escaned
- Rajiv Tayal
- Evan Shlofmitz
- Jennifer A. Rymer
- Morton J. Kern
Institutions
- Universidad Complutense de Madrid (ES)
- Van Andel Institute (US)
- Abbott Northwestern Hospital (US)
- Allina Health (US)
- University of California, Irvine (US)
- VA Palo Alto Health Care System (US)
- Henry Ford Hospital (US)
- Hospital Clínico San Carlos (ES)
- St. Francis Hospital (US)
- Instituto de Investigación Sanitaria del Hospital Clínico San Carlos (ES)
- Valley Health System (US)
- Onze Lieve Vrouwziekenhuis Hospital (BE)
- New York Institute of Technology (US)
- King Fahd Armed Forces Hospital (SA)
- Heart Hospital Baylor Plano (US)
- Duke Medical Center (US)
- Minneapolis Heart Institute Foundation (US)
- Cardiovascular Research Foundation (US)
- Hackensack Meridian Health (US)
- VA Long Beach Healthcare System (US)
- New York University (US)
- Stanford University (US)
- Icahn School of Medicine at Mount Sinai (US)
Publication Details
- Journal
- Journal of the Society for Cardiovascular Angiography & Interventions
- Published
- 2026-02-03
- DOI
- https://doi.org/10.1016/j.jscai.2025.104156
- Citations
- 2
- Primary Topic
- Coronary Interventions and Diagnostics
- Type
- article
- Field-Weighted Citation Impact
- 78.29