An MRI‐based macro‐ and microstructural neuroimaging‐wide association study of subsequent cognitive impairment
Longitudinal alterations in WM microstructural integrity were most strongly associated with future impairment, highlighting the importance of early WM changes in the development of MCI and dementia.
Authors
- Sridhar Kandala
- Tugce Duran
- Christos Davatzikos
- Bennett A. Landman
- Guray Erus
- Keenan A. Walker
- Abhay Moghekar
- Susan M. Resnick
- Yang An
- Luigi Ferrucci
- Murat Bilgel
Institutions
- National Institutes of Health (US)
- Johns Hopkins University (US)
- Vanderbilt University (US)
- Johns Hopkins Medicine (US)
- National Institute on Aging (US)
- University of Pennsylvania (US)
Publication Details
- Journal
- Alzheimer s & Dementia
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1002/alz.71135
- Primary Topic
- Advanced Neuroimaging Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health