How We Sleep, How We Move, How Long We Expect to Live: An Integrative Review of Lifestyle Behaviors and Subjective Life Expectancy

<b>Background</b>: Sleep quality (SQ) and physical activity (PA) are among the strongest behavioral determinants of healthy aging, while dietary behavior and psychological factors act as complementary modulators of these relationships. Although each domain has been studied extensively, their combined influence on subjective life expectancy (SLE)-an individual's perceived likelihood of living to an advanced age-remains largely unexplored. <b>Methods</b>: This narrative review synthesizes evidence from sleep science, exercise physiology, behavioral medicine, and psychological aging. Literature published between January 2015 and 15 December 2025 was examined across PubMed, Scopus, and Web of Science using integrative keyword strategies. Studies addressing SQ, PA, circadian rhythms, psychological health, SLE, or aging-related outcomes were included. <b>Results</b>: The review identifies several converging pathways linking sleep and PA to aging trajectories. Sleep architecture, circadian stability, metabolic regulation, inflammatory balance, and autonomic function represent key biological mechanisms. PA contributes through improvements in mitochondrial efficiency, VO<sub>2</sub>max, muscle metabolism, and anti-inflammatory signaling (IL-6 as a myokine). Across studies, both sleep and PA strongly influence psychological health, health perception, and future-oriented expectations, within a broader lifestyle context supported by nutritional status and dietary quality. SLE emerges as a central psychological mediator that shapes motivation, adherence to health behaviors, and long-term health outcomes. Contextual moderators-including age, gender, socioeconomic status, cultural norms, and wearable technology engagement-further influence these relationships. <b>Conclusions</b>: SQ and PA form the core behavioral components of a dynamic system that is further shaped by dietary behavior and psychological well-being and centered on SLE. Our proposed integrative model positions SLE as a key psychological link between lifestyle behaviors and longevity. This framework is hypothesis-generating and requires empirical validation through future longitudinal and interventional studies, underscoring the need for multidomain research integrating behavioral, biological, nutritional and psychological indicators of aging.

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Publication Details

Journal
Nutrients
Published
2026-02-03
DOI
https://doi.org/10.3390/nu18030515
Primary Topic
Sleep and related disorders
Type
article
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article

How We Sleep, How We Move, How Long We Expect to Live: An Integrative Review of Lifestyle Behaviors and Subjective Life Expectancy

Cristina Văcărescu, Constantin-Tudor Luca, Oana Pătru, Andreea Bena et al.
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Sleep and related disorders
article

How We Sleep, How We Move, How Long We Expect to Live: An Integrative Review of Lifestyle Behaviors and Subjective Life Expectancy

Cristina Văcărescu, Constantin-Tudor Luca, Oana Pătru, Andreea Bena, Mirela Vîrtosu, Bogdan Enache, S A Luca, Andrei Păunescu, Andreea-Iulia Ciornei
article en

Abstract

<b>Background</b>: Sleep quality (SQ) and physical activity (PA) are among the strongest behavioral determinants of healthy aging, while dietary behavior and psychological factors act as complementary modulators of these relationships. Although each domain has been studied extensively, their combined influence on subjective life expectancy (SLE)-an individual's perceived likelihood of living to an advanced age-remains largely unexplored. <b>Methods</b>: This narrative review synthesizes evidence from sleep science, exercise physiology, behavioral medicine, and psychological aging. Literature published between January 2015 and 15 December 2025 was examined across PubMed, Scopus, and Web of Science using integrative keyword strategies. Studies addressing SQ, PA, circadian rhythms, psychological health, SLE, or aging-related outcomes were included. <b>Results</b>: The review identifies several converging pathways linking sleep and PA to aging trajectories. Sleep architecture, circadian stability, metabolic regulation, inflammatory balance, and autonomic function represent key biological mechanisms. PA contributes through improvements in mitochondrial efficiency, VO<sub>2</sub>max, muscle metabolism, and anti-inflammatory signaling (IL-6 as a myokine). Across studies, both sleep and PA strongly influence psychological health, health perception, and future-oriented expectations, within a broader lifestyle context supported by nutritional status and dietary quality. SLE emerges as a central psychological mediator that shapes motivation, adherence to health behaviors, and long-term health outcomes. Contextual moderators-including age, gender, socioeconomic status, cultural norms, and wearable technology engagement-further influence these relationships. <b>Conclusions</b>: SQ and PA form the core behavioral components of a dynamic system that is further shaped by dietary behavior and psychological well-being and centered on SLE. Our proposed integrative model positions SLE as a key psychological link between lifestyle behaviors and longevity. This framework is hypothesis-generating and requires empirical validation through future longitudinal and interventional studies, underscoring the need for multidomain research integrating behavioral, biological, nutritional and psychological indicators of aging.

NutrientsVol. 18(3)
Spitalul Clinic Judeţean de Urgenţă "Pius Brînzeu" Timişoara (RO), Victor Babeș University of Medicine and Pharmacy Timișoara (RO), Institute e-Austria Timisoara (RO)
Zero hunger
Openalex Percentile: Top 69%
Sleep and related disorders
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