Long-term patient experience with online MR-guided radiotherapy: adaptive versus non-adaptive workflow
Online plan adaptation at the MR-Linac increased treatment times and was associated with less favorable short-term patient-reported outcomes, yet it was delivered safely without compromising toxicity or oncologic outcomes. These results support adaptive MR-guided radiotherapy as a feasible and technically promising approach, while highlighting the need for further studies with validated PROMs and cost-benefit analyses to define its clinical value.
Authors
- Sebastian Regnery (ORCID: https://orcid.org/0000-0002-6820-884X)
- Jakob Liermann (ORCID: https://orcid.org/0000-0002-1445-1940)
- Laila Christina König
- Eva Meixner (ORCID: https://orcid.org/0000-0001-7087-9581)
- Sebastian Klüter (ORCID: https://orcid.org/0000-0003-3139-3444)
- Carolin Rippke (ORCID: https://orcid.org/0000-0002-6519-928X)
- Charlotte Herder-Wagner
- Juliane Hörner‐Rieber (ORCID: https://orcid.org/0000-0003-3911-4438)
- Fabian Weykamp (ORCID: https://orcid.org/0000-0003-1731-7090)
- Philipp Hoegen-Saßmannshausen
- Jürgen Debus
- Kristin Lang
- C. Katharina Renkamp
Institutions
- German Cancer Research Center (DE)
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- Düsseldorf University Hospital (DE)
- Heidelberger Institut für Radioonkologie (DE)
- National Center for Tumor Diseases (DE)
- Heidelberg (Poland) (PL)
- Heinrich Heine University Düsseldorf (DE)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2026-02-03
- DOI
- https://doi.org/10.3389/fonc.2026.1700649
- Primary Topic
- Advanced Radiotherapy Techniques
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Deutsche Forschungsgemeinschaft