Polygenic risk scores for premagnetic resonance imaging risk stratification in men with clinically suspected prostate cancer
Genotype-informed risk stratification using PCa-PRS could increase the proportion of cancer-suspicious findings at MRI, while identifying those who could safely avoid unnecessary MRI.
Authors
- Tobias Penzkofer (ORCID: https://orcid.org/0000-0001-9591-8575)
- Patrick Asbach (ORCID: https://orcid.org/0000-0002-6885-3283)
- Charlie Alexander Hamm (ORCID: https://orcid.org/0000-0003-4104-4758)
- Frank König (ORCID: https://orcid.org/0000-0002-6225-6103)
- Carla Maria Hansen (ORCID: https://orcid.org/0009-0001-6180-506X)
- S. Ripke
- Georg Lukas Baumgärtner
- Alice Braun
- Anwar R Padhani
- Max P Fischer
- Marcus R Makowski
Institutions
- Humboldt-Universität zu Berlin (DE)
- Klinikum Magdeburg (DE)
- Mount Vernon Cancer Centre (GB)
- University Hospital Magdeburg (DE)
- Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE)
- Technical University of Munich (DE)
Publication Details
- Journal
- JNCI Journal of the National Cancer Institute
- Published
- 2026-01-28
- DOI
- https://doi.org/10.1093/jnci/djag027
- Primary Topic
- Prostate Cancer Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00