Mixed Adenoneuroendocrine Carcinoma ( <scp>MANEC</scp> ) of the Stomach: A Case Report in a 52‐Year‐Old Male Following Total <scp>D2</scp> Gastrectomy

Gastric MANEC (gMANEC) is a rare tumor composed of at least 30% each adenocarcinoma and neuroendocrine carcinoma (NEC) components. A 52-year-old male underwent total D2 gastrectomy for gastric cancer. Final pathology revealed MANEC. We compare outcomes and mortality rates between gastric MANEC and conventional adenocarcinoma. MANEC has poorer disease-free survival (DFS) and post-recurrence survival (PRS), and higher risk of distant recurrence, compared with clear adenocarcinoma. Rigorous follow-up and adjuvant therapy tailored to the more aggressive component are advised.