Neural Fields for Highly Accelerated 2D Cine Phase Contrast MRI

2D cine phase contrast (CPC) MRI provides quantitative information on blood velocity and flow within the human vasculature. However, data acquisition is time-consuming, motivating the reconstruction of the velocity field from undersampled measurements to reduce scan times. In this work, neural fields are proposed as a continuous spatiotemporal parametrization of complex-valued images, jointly modeling magnitude and phase across multiple echoes to enable velocity estimation, and leveraging their inductive bias for the reconstruction of the velocity data. Additionally, to compensate for the oversmoothing tendency observed in neural-field reconstructions under severe undersampling, a simple voxel-based postprocessing step is introduced. The method is validated numerically in Cartesian and radial k-space with both high and low temporal resolution data. This approach achieves accurate reconstructions at high acceleration factors, with low errors even at 32 <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:semantics><mml:mo>×</mml:mo> <mml:annotation>$\times$</mml:annotation></mml:semantics> </mml:math> and 64 <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:semantics><mml:mo>×</mml:mo> <mml:annotation>$\times$</mml:annotation></mml:semantics> </mml:math> undersampling for the high temporal resolution data, and 16 <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:semantics><mml:mo>×</mml:mo> <mml:annotation>$\times$</mml:annotation></mml:semantics> </mml:math> for the low temporal resolution data, and consistently outperforms classical locally low-rank regularized voxel-based methods in both flow estimates and anatomical depiction.

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Publication Details

Journal
Advanced Science
Published
2026-02-03
DOI
https://doi.org/10.1002/advs.202519788
Primary Topic
Advanced X-ray Imaging Techniques
Type
article
Field-Weighted Citation Impact
0.00

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article

Neural Fields for Highly Accelerated 2D Cine Phase Contrast MRI

Carolin M. Pirkl, Carola‐Bibiane Schönlieb, Mary A. McLean, Timo Schirmer et al.
Advanced Science
Advanced X-ray Imaging Techniques
article

Neural Fields for Highly Accelerated 2D Cine Phase Contrast MRI

Carolin M. Pirkl, Carola‐Bibiane Schönlieb, Mary A. McLean, Timo Schirmer, Matthias J. Ehrhardt, Florian Wiesinger, Pablo Arratia, Martin J. Graves
article en

Abstract

2D cine phase contrast (CPC) MRI provides quantitative information on blood velocity and flow within the human vasculature. However, data acquisition is time-consuming, motivating the reconstruction of the velocity field from undersampled measurements to reduce scan times. In this work, neural fields are proposed as a continuous spatiotemporal parametrization of complex-valued images, jointly modeling magnitude and phase across multiple echoes to enable velocity estimation, and leveraging their inductive bias for the reconstruction of the velocity data. Additionally, to compensate for the oversmoothing tendency observed in neural-field reconstructions under severe undersampling, a simple voxel-based postprocessing step is introduced. The method is validated numerically in Cartesian and radial k-space with both high and low temporal resolution data. This approach achieves accurate reconstructions at high acceleration factors, with low errors even at 32 <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:semantics><mml:mo>×</mml:mo> <mml:annotation>$\times$</mml:annotation></mml:semantics> </mml:math> and 64 <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:semantics><mml:mo>×</mml:mo> <mml:annotation>$\times$</mml:annotation></mml:semantics> </mml:math> undersampling for the high temporal resolution data, and 16 <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML"><mml:semantics><mml:mo>×</mml:mo> <mml:annotation>$\times$</mml:annotation></mml:semantics> </mml:math> for the low temporal resolution data, and consistently outperforms classical locally low-rank regularized voxel-based methods in both flow estimates and anatomical depiction.

Advanced Science
General Electric (Spain) (ES), University of Cambridge (GB), University of Bath (GB)
Cancer Research UK, National Institute for Health and Care Research, Department of Health and Social Care, European Commission, Imperial Experimental Cancer Medicine Centre, Engineering and Physical Sciences Research Council, NIHR Cambridge Biomedical Research Centre, Centre for Doctoral Training in Statistical Applied Mathematics, University of Bath
Openalex Percentile: Top 68%
Advanced X-ray Imaging Techniques
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