Comparative clinical features of antibiotic-associated Kounis syndrome and non-Kounis allergic coronary events: a disproportionality analysis using U.S. Food and Drug Administration Adverse Event Reporting System

These exploratory findings indicate that non-KS allergic coronary events, characterized by higher comorbidities, mortality, and proportion of cases reporting the use of quinolones or aminoglycosides, may suggest a potential relationship between non-KS coronary events and KS underdiagnosis, warranting further prospective investigation.

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Publication Details

Journal
Journal of Pharmaceutical Health Care and Sciences
Published
2026-02-03
DOI
https://doi.org/10.1186/s40780-026-00545-7
Primary Topic
Food Allergy and Anaphylaxis Research
Type
article
Field-Weighted Citation Impact
0.00
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article

Comparative clinical features of antibiotic-associated Kounis syndrome and non-Kounis allergic coronary events: a disproportionality analysis using U.S. Food and Drug Administration Adverse Event Reporting System

Yoshiko Une, Yutaro Mukai, Kouichi Hosomi, Kaori Yamanishi et al.
Journal of Pharmaceutical Health Care and Sciences
Food Allergy and Anaphylaxis Research
article

Comparative clinical features of antibiotic-associated Kounis syndrome and non-Kounis allergic coronary events: a disproportionality analysis using U.S. Food and Drug Administration Adverse Event Reporting System

Yoshiko Une, Yutaro Mukai, Kouichi Hosomi, Kaori Yamanishi, Ichiro Nakakura, N O'Hara, Satoshi Yokoyama, Takaya Uno, Atsuki Hosoda
article en

Abstract

These exploratory findings indicate that non-KS allergic coronary events, characterized by higher comorbidities, mortality, and proportion of cases reporting the use of quinolones or aminoglycosides, may suggest a potential relationship between non-KS coronary events and KS underdiagnosis, warranting further prospective investigation.

Journal of Pharmaceutical Health Care and SciencesVol. 12(1)
National Cerebral and Cardiovascular Center (JP), Kindai University (JP)
Good health and well-being
Openalex Percentile: Top 74%
Food Allergy and Anaphylaxis Research
DOIOpen Access PDFOpenAlex
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Comparative clinical features of antibiotic-associated Kounis syndrome and non-Kounis allergic coronary events: a disproportionality analysis using U.S. Food and Drug Administration Adverse Event Reporting System — Yoshiko Une, Yutaro Mukai, et al. · Journal of Pharmaceutical Health Care and Sciences (2026) | TGRS Research Map | TGRS