Concurrent pulmonary candidiasis and tuberculosis in type 2 diabetes mellitus: immune pathogenesis and multidisciplinary management challenges: a case report

In patients with diabetes and pulmonary lesions, concomitant or sequential fungal and tuberculous infections should be actively sought with stepwise microbiology (including bronchoalveolar lavage and tissue‑based methods) and early molecular testing (metagenomic next-generation sequencing/Xpert). Steroid exposure for organizing pneumonia may worsen or unmask tuberculosis and must be weighed against infectious risk. Multidisciplinary care (endocrinology-pulmonology-infectious diseases) and rigorous glucose control are essential.

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Publication Details

Journal
Journal of Medical Case Reports
Published
2026-02-02
DOI
https://doi.org/10.1186/s13256-026-05853-y
Primary Topic
Tuberculosis Research and Epidemiology
Type
article
Field-Weighted Citation Impact
0.00
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article

Concurrent pulmonary candidiasis and tuberculosis in type 2 diabetes mellitus: immune pathogenesis and multidisciplinary management challenges: a case report

Feng Wang, Yuting Li, Aibo Zheng, Wenjun Li et al.
Journal of Medical Case Reports
Tuberculosis Research and Epidemiology
article

Concurrent pulmonary candidiasis and tuberculosis in type 2 diabetes mellitus: immune pathogenesis and multidisciplinary management challenges: a case report

Feng Wang, Yuting Li, Aibo Zheng, Wenjun Li, Jie Gan, Yan Jin, Wei Wu
article en

Abstract

In patients with diabetes and pulmonary lesions, concomitant or sequential fungal and tuberculous infections should be actively sought with stepwise microbiology (including bronchoalveolar lavage and tissue‑based methods) and early molecular testing (metagenomic next-generation sequencing/Xpert). Steroid exposure for organizing pneumonia may worsen or unmask tuberculosis and must be weighed against infectious risk. Multidisciplinary care (endocrinology-pulmonology-infectious diseases) and rigorous glucose control are essential.

Journal of Medical Case ReportsVol. 20(1)
Zigong First People's Hospital (CN)
Good health and well-being
Openalex Percentile: Top 66%
Tuberculosis Research and Epidemiology
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