Computed Tomography Radiomic Signatures Associated With Neutrophil Extracellular Trap Enrichment and First‐Pass Outcome in Ischemic Stroke Thrombi
NET enrichment in clots is associated with reduced mFPE success. With further validation, RFs extracted from prethrombectomy computed tomography imaging may serve as noninvasive biomarkers of clot NET content to aid in preprocedural MT decision-making.
Authors
- Briana A. Santo (ORCID: https://orcid.org/0000-0001-8850-2985)
- Kerry E. Poppenberg (ORCID: https://orcid.org/0000-0002-1748-887X)
- Seyyed Sarayi
- John Kolega (ORCID: https://orcid.org/0000-0001-6933-8681)
- Vinay Jaikumar (ORCID: https://orcid.org/0000-0002-6677-1858)
- Tatsat R. Patel (ORCID: https://orcid.org/0000-0002-4074-6822)
- TaJania D. Jenkins
- Sarah Balghonaim
- Alexandria Scotti
- Adnan H. Siddiqui
- Vincent M. Tutino
- Elad I. Levy
Institutions
- Canon (United States) (US)
- University at Buffalo, State University of New York (US)
Publication Details
- Journal
- Journal of the American Heart Association
- Published
- 2026-02-03
- DOI
- https://doi.org/10.1161/jaha.125.046619
- Primary Topic
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00