Prognostic and Clinicopathological Evaluation of NOTCH-1 Expression in Endometrial Carcinoma

NOTCH-1 expression was not associated with key clinicopathological or survival parameters in this cohort. While some molecular correlations were observed, NOTCH-1 does not appear to have strong prognostic utility in EC. Further research integrating molecular classification and long-term follow-up is needed to clarify its potential role in tumor biology.

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Publication Details

Journal
Applied immunohistochemistry & molecular morphology
Published
2026-02-04
DOI
https://doi.org/10.1097/pai.0000000000001305
Primary Topic
Cerebrovascular and genetic disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Prognostic and Clinicopathological Evaluation of NOTCH-1 Expression in Endometrial Carcinoma

Yeliz Arman Karakaya, Nursinem Alkan Vurğun
Applied immunohistochemistry & molecular morphology
Cerebrovascular and genetic disorders
article

Prognostic and Clinicopathological Evaluation of NOTCH-1 Expression in Endometrial Carcinoma

Yeliz Arman Karakaya, Nursinem Alkan Vurğun
article en

Abstract

NOTCH-1 expression was not associated with key clinicopathological or survival parameters in this cohort. While some molecular correlations were observed, NOTCH-1 does not appear to have strong prognostic utility in EC. Further research integrating molecular classification and long-term follow-up is needed to clarify its potential role in tumor biology.

Applied immunohistochemistry & molecular morphology
Hakkari University (TR), Pamukkale University (TR)
Good health and well-being
Openalex Percentile: Top 69%
Cerebrovascular and genetic disorders
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