Quercetin-Loaded Avocado Oil Nanoemulsion Reverses High-fat and High-carbohydrate Diet-Induced Testicular Dysfunction: Role of Oxidative Stress and NPY Signaling in a Randomized Trial

The combined NAOQu formulation showed greater protective effects than Qu or AO alone, suggesting a synergistic effect. These findings highlight the potential of avocado oil-based nanoemulsion as an effective delivery system for Qu, offering a novel therapeutic strategy to counteract HF-induced male reproductive dysfunction and metabolic disease.

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Publication Details

Journal
Iranian journal of pharmaceutical research
Published
2025-12-31
DOI
https://doi.org/10.5812/ijpr-165025
Primary Topic
Coconut Research and Applications
Type
article
Field-Weighted Citation Impact
0.00
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article

Quercetin-Loaded Avocado Oil Nanoemulsion Reverses High-fat and High-carbohydrate Diet-Induced Testicular Dysfunction: Role of Oxidative Stress and NPY Signaling in a Randomized Trial

Saeed Hesaraki, Hamidreza Mazangi, Negar Panahi, Shahabeddin Safi
Iranian journal of pharmaceutical research
Coconut Research and Applications
article

Quercetin-Loaded Avocado Oil Nanoemulsion Reverses High-fat and High-carbohydrate Diet-Induced Testicular Dysfunction: Role of Oxidative Stress and NPY Signaling in a Randomized Trial

Saeed Hesaraki, Hamidreza Mazangi, Negar Panahi, Shahabeddin Safi
article en

Abstract

The combined NAOQu formulation showed greater protective effects than Qu or AO alone, suggesting a synergistic effect. These findings highlight the potential of avocado oil-based nanoemulsion as an effective delivery system for Qu, offering a novel therapeutic strategy to counteract HF-induced male reproductive dysfunction and metabolic disease.

Iranian journal of pharmaceutical researchVol. 24(1)
Islamic Azad University, Tehran (IR), Islamic Azad University South Tehran Branch (IR)
Openalex Percentile: Top 42%
Coconut Research and Applications
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