Zinc supplementation and 60-day mortality in patients receiving total parenteral nutrition: a single-center experience

In this single-center retrospective cohort, higher zinc supplementation (≥2 mg/day) during TPN administration was associated with lower 60-day mortality. These findings highlight the potential clinical relevance of zinc dosing in TPN regimens and warrant prospective validation.

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Publication Details

Journal
Frontiers in Nutrition
Published
2026-02-04
DOI
https://doi.org/10.3389/fnut.2026.1735455
Primary Topic
Clinical Nutrition and Gastroenterology
Type
article
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article

Zinc supplementation and 60-day mortality in patients receiving total parenteral nutrition: a single-center experience

Jheng-Yan Wu, M. -T. Liu, Chia-Yin Kuo, Hwung-Chung Lee
Frontiers in Nutrition
Clinical Nutrition and Gastroenterology
article

Zinc supplementation and 60-day mortality in patients receiving total parenteral nutrition: a single-center experience

Jheng-Yan Wu, M. -T. Liu, Chia-Yin Kuo, Hwung-Chung Lee
article en

Abstract

In this single-center retrospective cohort, higher zinc supplementation (≥2 mg/day) during TPN administration was associated with lower 60-day mortality. These findings highlight the potential clinical relevance of zinc dosing in TPN regimens and warrant prospective validation.

Frontiers in NutritionVol. 13
Chi Mei Medical Center (TW), Chang Jung Christian University (TW), National Cheng Kung University (TW), Southern Taiwan University of Science and Technology (TW)
Zero hunger
Openalex Percentile: Top 67%
Clinical Nutrition and Gastroenterology
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