Comparison of Train-of-Four Versus No Train-of-Four Monitoring of Neuromuscular Blockade on Drug Consumption for Acute Respiratory Distress Syndrome

This study assesses drug utilization when comparing TOF-guided NMB titration with clinical assessment alone in the modern ARDS era. Utilization of clinical assessment alone without TOF monitoring for CI CIS resulted in significantly reduced drug utilization and costs. Further studies are needed to assess the impact of clinical assessment alone on improvement of oxygenation.

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Publication Details

Journal
Annals of Pharmacotherapy
Published
2026-02-02
DOI
https://doi.org/10.1177/10600280251414669
Primary Topic
Anesthesia and Sedative Agents
Type
article
Field-Weighted Citation Impact
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article

Comparison of Train-of-Four Versus No Train-of-Four Monitoring of Neuromuscular Blockade on Drug Consumption for Acute Respiratory Distress Syndrome

Karl Yaeger, Ryan Rivosecchi, Lara Groetzinger, Julie Clarkson et al.
Annals of Pharmacotherapy
Anesthesia and Sedative Agents
article

Comparison of Train-of-Four Versus No Train-of-Four Monitoring of Neuromuscular Blockade on Drug Consumption for Acute Respiratory Distress Syndrome

Karl Yaeger, Ryan Rivosecchi, Lara Groetzinger, Julie Clarkson, Phillip E. Lamberty
article en

Abstract

This study assesses drug utilization when comparing TOF-guided NMB titration with clinical assessment alone in the modern ARDS era. Utilization of clinical assessment alone without TOF monitoring for CI CIS resulted in significantly reduced drug utilization and costs. Further studies are needed to assess the impact of clinical assessment alone on improvement of oxygenation.

Annals of Pharmacotherapy
Strong Memorial Hospital (US), University of Rochester Medical Center (US), Presbyterian Hospital (US), UPMC Presbyterian (US), University of Pittsburgh Medical Center (US)
Good health and well-being
Openalex Percentile: Top 65%
Anesthesia and Sedative Agents
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Comparison of Train-of-Four Versus No Train-of-Four Monitoring of Neuromuscular Blockade on Drug Consumption for Acute Respiratory Distress Syndrome — Karl Yaeger, Ryan Rivosecchi, et al. · Annals of Pharmacotherapy (2026) | TGRS Research Map | TGRS