Correlation between sarcopenia and changes in oligodendrocyte lineage cells in the brains of Alzheimer's disease model mice

Hindlimb immobilization-induced sarcopenia correlated with slow-to-fast fiber transformation, reduced OPCs proliferation, and enhanced neuroinflammation. This study highlights the importance of sarcopenia in the progression of AD-related white matter pathology.

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Publication Details

Journal
Experimental Gerontology
Published
2026-02-04
DOI
https://doi.org/10.1016/j.exger.2026.113057
Primary Topic
Neurogenesis and neuroplasticity mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

Correlation between sarcopenia and changes in oligodendrocyte lineage cells in the brains of Alzheimer's disease model mice

Quanhong Ma, Shanwen Liu, Yu-Tong Du, Er-lei Wang et al.
Experimental Gerontology
Neurogenesis and neuroplasticity mechanisms
article

Correlation between sarcopenia and changes in oligodendrocyte lineage cells in the brains of Alzheimer's disease model mice

Quanhong Ma, Shanwen Liu, Yu-Tong Du, Er-lei Wang, Lin-lin Yao, Hua Hu, Hong Chen, Jia-wen Zhu, Fang-bo Li, Xiao-ting Ma, Yan-yun Sun, Chun-feng Liu, Lin-yi Zheng, Qi Zeng
article en

Abstract

Hindlimb immobilization-induced sarcopenia correlated with slow-to-fast fiber transformation, reduced OPCs proliferation, and enhanced neuroinflammation. This study highlights the importance of sarcopenia in the progression of AD-related white matter pathology.

Experimental GerontologyVol. 215
Soochow University (CN), Second Affiliated Hospital of Soochow University (CN)
Good health and well-being
Openalex Percentile: Top 74%
Neurogenesis and neuroplasticity mechanisms
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