An individual participant data network meta-analysis of the APOSTEL trials on the effect of tocolysis in threatened preterm birth between 30–33+6 weeks of gestation in twin pregnancies

No clear benefit of nifedipine or atosiban over placebo on neonatal outcomes in twin pregnancies with threatened preterm birth between 30<sup>+0</sup> and 33<sup>+6</sup> weeks was found.

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Publication Details

Journal
European Journal of Obstetrics & Gynecology and Reproductive Biology
Published
2026-02-04
DOI
https://doi.org/10.1016/j.ejogrb.2026.114989
Primary Topic
Preterm Birth and Chorioamnionitis
Type
article
Field-Weighted Citation Impact
0.00
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article

An individual participant data network meta-analysis of the APOSTEL trials on the effect of tocolysis in threatened preterm birth between 30–33+6 weeks of gestation in twin pregnancies

M.A. Oudijk, L.I. van der Windt, A.H. van Kaam, C. Roos et al.
European Journal of Obstetrics & Gynecology and Reproductive Biology
Preterm Birth and Chorioamnionitis
article

An individual participant data network meta-analysis of the APOSTEL trials on the effect of tocolysis in threatened preterm birth between 30–33+6 weeks of gestation in twin pregnancies

M.A. Oudijk, L.I. van der Windt, A.H. van Kaam, C. Roos, L. van Gils, E. Pajkrt
article en

Abstract

No clear benefit of nifedipine or atosiban over placebo on neonatal outcomes in twin pregnancies with threatened preterm birth between 30<sup>+0</sup> and 33<sup>+6</sup> weeks was found.

European Journal of Obstetrics & Gynecology and Reproductive BiologyVol. 319
Emma Kinderziekenhuis (NL), Amsterdam Neuroscience (NL), Amsterdam University Medical Centers (NL), Vrije Universiteit Amsterdam (NL), University of Amsterdam (NL)
Openalex Percentile: Top 67%
Preterm Birth and Chorioamnionitis
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