Hypercapnic acidosis affects in vitro lung infection response in a pathogen-specific manner
HCA condition differentially influence host responses depending on the infectious pathogen, compromising the barrier function and prolonging lung inflammation with differences according to time culture, which could benefit bacterial persistence.
Authors
- Elena Campaña-Duel (ORCID: https://orcid.org/0000-0002-0658-6255)
- Aina Areny‐Balagueró (ORCID: https://orcid.org/0000-0001-9611-1781)
- Laia Fernández‐Barat (ORCID: https://orcid.org/0000-0001-7528-9636)
- Lluís Blanch
- M. Camprubí-Rimblas
- Diana Fuertes-Bailón
- Luis Morales-Quinteros
- Antoni Torres
Institutions
- Centro de Investigación Biomédica en Red de Enfermedades Respiratorias (ES)
- Vall d'Hebron Institut de Recerca (ES)
- Corporació Sanitària Parc Taulí (ES)
- Hospital Universitari Sagrat Cor (ES)
- Institute of Research and Innovation Parc Tauli (ES)
- Pulmonary Associates (US)
- Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES)
- Universitat de Barcelona (ES)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2026-02-03
- DOI
- https://doi.org/10.3389/fcimb.2025.1708427
- Primary Topic
- Respiratory Support and Mechanisms
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Centres de Recerca de Catalunya
- Sociedad Española de Neumología y Cirugía Torácica
- European Society of Intensive Care Medicine
- Instituto de Salud Carlos III