Steroidogenic Factor 1 ( <scp>SF1</scp> ) Immunohistochemical Stain Is Sensitive and Specific for the Cytopathologic Identification of Intrapancreatic Ectopic Splenic Tissue
While CD8 and SF1 are comparable in their sensitivity, SF1 has benefits in cytologic samples. As a nuclear stain, SF1 is more easily interpreted and better suited for cell transfers. SF1 also eliminates the background CD8+ T cell staining that can be present in lymphoid tissue. Overall, utilization of SF1 can be beneficial in the cytologic workup of an intrapancreatic accessory spleen.
Authors
- Omer Abdelaziz Mohammed Saeed (ORCID: https://orcid.org/0000-0002-4584-9222)
- Hector Mesa (ORCID: https://orcid.org/0000-0003-1833-4642)
- J Muldoon
- Adeyinka Akinsanya
- Bin Yang (ORCID: https://orcid.org/0000-0003-3817-6792)
- Mohamed Mustafa
Institutions
- University of Maryland, Baltimore (US)
- Cleveland Clinic Lerner College of Medicine (US)
- Indiana University School of Medicine
- Indiana University – Purdue University Indianapolis (US)
Publication Details
- Journal
- Diagnostic Cytopathology
- Published
- 2026-02-02
- DOI
- https://doi.org/10.1002/dc.70093
- Primary Topic
- Abdominal Trauma and Injuries
- Type
- article
- Field-Weighted Citation Impact
- 0.00