Differential expression of complement Properdin and Factor H in the placentae and umbilical cords of mothers with Preeclampsia, Gestational Diabetes Mellitus and Recurrent Pregnancy Loss
The observed elevated properdin level can contribute to the heightened inflammatory response in PE, GDM and RPL placentae. Low FH and high C3 and C5 in the placenta possibly suggests dysregulated complement activation in PE and RPL.
Authors
- Uday Kishore (ORCID: https://orcid.org/0000-0002-6033-6759)
- Hadida Yasmin (ORCID: https://orcid.org/0000-0001-7292-3937)
- Shyama Prasad Saha (ORCID: https://orcid.org/0000-0003-4528-7052)
- Tamali Roy
- Taruna Madan
- Ananya Das
- Nabanita Chatterjee
- Rajib Prasad
Institutions
- United Arab Emirates University (AE)
- Cooch Behar Panchanan Barma University (IN)
- Chittaranjan National Cancer Institute (IN)
- Indian Council of Medical Research (IN)
- Narayan Medical College and Hospital (IN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2026-02-03
- DOI
- https://doi.org/10.3389/fimmu.2025.1731251
- Citations
- 1
- Primary Topic
- Pregnancy and preeclampsia studies
- Type
- article
- Field-Weighted Citation Impact
- 41.10