Cytokine mRNA-based therapy alleviates dendritic cell and T cell paucity to eliminate aggressive pancreatic cancer in preclinical mouse models
This work was supported by Ministry of Education, Culture, Sports, Science and Technology of Japan (MEXT), Japan Agency for Medical Research and Development (AMED), and the Princess Takamatsu Cancer Research Fund.
Authors
- Shu Tsukihara (ORCID: https://orcid.org/0000-0003-2537-719X)
- Megumi Kato (ORCID: https://orcid.org/0000-0002-4930-4852)
- Kentaro Umemura (ORCID: https://orcid.org/0000-0003-1259-5438)
- Atsushi Kamachi (ORCID: https://orcid.org/0000-0002-4012-0459)
- Yoshiya Ishikawa (ORCID: https://orcid.org/0000-0002-3348-5652)
- Yoshiaki Tanji (ORCID: https://orcid.org/0009-0004-6585-3220)
- ERIKA MOCHIZUKI
- Koya Yasukawa (ORCID: https://orcid.org/0000-0002-3643-0921)
- Daisuke Ban Daisuke Ban
- Atsushi Nara (ORCID: https://orcid.org/0000-0001-9233-8911)
- Shinji Tanaka
- Megumi Hatano
- Kohei Okazaki
- Keita Kodera
- Yosuke Igarashi
- Masahiro Yamane
- Shu Shimada
- Toru Ikegami
- Yuki Mochida
- Yoshimitsu Akiyama
- Satoshi Uchida
Institutions
- Tokyo Institute of Technology (JP)
- Jikei University School of Medicine (JP)
- Shinshu University (JP)
- Tokyo College of Music (JP)
- Tokyo Institute of Psychiatry (JP)
- Institute of Medicinal Molecular Design (JP)
- Advanced Medical Research Institute (US)
- The University of Tokyo (JP)
Publication Details
- Journal
- EBioMedicine
- Published
- 2026-02-03
- DOI
- https://doi.org/10.1016/j.ebiom.2026.106137
- Primary Topic
- Immunotherapy and Immune Responses
- Type
- article
- Field-Weighted Citation Impact
- 0.00