Dihydromyricetin Modulates Neuropathic Pain and Depression: A Correlation with Hippocampal Vascular Endothelial Growth Factor in Mice

This study elucidates that DHM alleviates neuropathic pain and depressive-like behavior, potentially be related to the upregulation of the VEGFA/VEGFR2 signaling pathway and subsequent attenuation of neuroinflammation.

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Publication Details

Journal
Journal of Inflammation Research
Published
2026-02-01
DOI
https://doi.org/10.2147/jir.s538350
Primary Topic
Medicinal plant effects and applications
Type
article
Field-Weighted Citation Impact
0.00

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article

Dihydromyricetin Modulates Neuropathic Pain and Depression: A Correlation with Hippocampal Vascular Endothelial Growth Factor in Mice

Chen Zuo-ming, Li Wan, Si-En Li, Hua-Feng Liu et al.
Journal of Inflammation Research
Medicinal plant effects and applications
article

Dihydromyricetin Modulates Neuropathic Pain and Depression: A Correlation with Hippocampal Vascular Endothelial Growth Factor in Mice

Chen Zuo-ming, Li Wan, Si-En Li, Hua-Feng Liu, Yu Zheng, Liu-Qing Ye, Xiao-Hui Chen, Yu Fei Wang, Tian Li, Wen-Xin Zeng
article en

Abstract

This study elucidates that DHM alleviates neuropathic pain and depressive-like behavior, potentially be related to the upregulation of the VEGFA/VEGFR2 signaling pathway and subsequent attenuation of neuroinflammation.

Journal of Inflammation ResearchVol. Volume 19
Second Affiliated Hospital of Guangzhou Medical University (CN), Guangzhou Medical University (CN)
National Natural Science Foundation of China
Good health and well-being
Openalex Percentile: Top 66%
Medicinal plant effects and applications
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