Safety and Efficacy of Combining Metastasis-Directed Stereotactic Ablative Radiation Therapy with Tyrosine Kinase Inhibitors Versus Immune Checkpoint Inhibitors in Metastatic Hepatocellular Carcinoma
Metastasis-directed SABR combined with either TKIs or ICIs was generally well tolerated in patients with extrahepatic metastatic HCC, with rare grade 3 late AEs; grade ≥2 late AEs were more frequent with SABR plus ICIs, warranting prospective evaluation.
Authors
- Myung Ji Goh (ORCID: https://orcid.org/0000-0001-9467-9664)
- N. Kim
- Eunyeong Yang
- Yong-Han Paik
- Moon Seok Choi
- Joon Hyeok Lee
- Jung Yong Hong
- Wonseok Kang
- Dong Hyun Sinn
- Hee Chul Park
- Byeong Geun Song
- Jeong Il Yu
- Geum-Youn Gwak
Institutions
- Samsung Medical Center (KR)
- Sungkyunkwan University (KR)
- Baewha Women's University (KR)
Publication Details
- Journal
- Cancer Research and Treatment
- Published
- 2026-02-03
- DOI
- https://doi.org/10.4143/crt.2025.966
- Primary Topic
- Hepatocellular Carcinoma Treatment and Prognosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00