Platelets accelerate endoplasmic reticulum stress and promote hepatic steatosis

This paper shows that blood platelets are capable of regulating specific metabolic functions in liver cells (so-called ER stress) and thereby contribute to the development of hepatic steatosis.

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Publication Details

Journal
JHEP Reports
Published
2026-02-04
DOI
https://doi.org/10.1016/j.jhepr.2026.101767
Primary Topic
Liver Disease Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Platelets accelerate endoplasmic reticulum stress and promote hepatic steatosis

Hanna Engelke, Manuel Salzmann, Ulrich Stelzl, Bernhard Nieswandt et al.
JHEP Reports
Liver Disease Diagnosis and Treatment
article

Platelets accelerate endoplasmic reticulum stress and promote hepatic steatosis

Hanna Engelke, Manuel Salzmann, Ulrich Stelzl, Bernhard Nieswandt, Alice Assinger, Waltraud C. Schrottmaier, Martina Derler, Anderson M. Campos, Marion Mußbacher, Johannes A. Schmid, S. C. Beck, Natalia Kunowska, Elisabeth Ableitner, Elisabeth Annerer, Twisha Dube, Dagmar Kolb
article en

Abstract

This paper shows that blood platelets are capable of regulating specific metabolic functions in liver cells (so-called ER stress) and thereby contribute to the development of hepatic steatosis.

JHEP ReportsVol. 8(4)
University of Graz (AT), Medical University of Graz (AT), University of Würzburg (DE), BioTechMed-Graz (AT), Universitätsklinikum Würzburg (DE), Medical University of Vienna (AT)
Zero hunger
Openalex Percentile: Top 67%
Liver Disease Diagnosis and Treatment
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Platelets accelerate endoplasmic reticulum stress and promote hepatic steatosis — Hanna Engelke, Manuel Salzmann, et al. · JHEP Reports (2026) | TGRS Research Map | TGRS