Vascular Obstruction Scoring on Dual-energy CT, Cone-beam CT and Digital Subtraction Angiography: Correlation with Invasive Hemodynamics in Chronic Thromboembolic Pulmonary Hypertension

This study presents a systematic application of a unified vascular obstruction scoring system across dual-energy CT, cone-beam CT, and digital subtraction angiography in patients with chronic thromboembolic pulmonary hypertension. The results demonstrate significant correlations with invasive hemodynamic parameters, with dual-energy CT and cone-beam CT providing higher reproducibility than angiography. These findings support the use of a standardized scoring framework to enable consistent multimodality assessment, improve reproducibility in structured multimodality imaging assessment, and facilitate cross-institutional comparisons in chronic thromboembolic pulmonary hypertension.

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Publication Details

Journal
Academic Radiology
Published
2026-02-01
DOI
https://doi.org/10.1016/j.acra.2026.01.019
Primary Topic
Pulmonary Hypertension Research and Treatments
Type
article
Field-Weighted Citation Impact
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article

Vascular Obstruction Scoring on Dual-energy CT, Cone-beam CT and Digital Subtraction Angiography: Correlation with Invasive Hemodynamics in Chronic Thromboembolic Pulmonary Hypertension

Alfredo Páez-Carpio, Llúria Cornellas, Ivan Vollmer, Blanca Domenech-Ximenos et al.
Academic Radiology
Pulmonary Hypertension Research and Treatments
article

Vascular Obstruction Scoring on Dual-energy CT, Cone-beam CT and Digital Subtraction Angiography: Correlation with Invasive Hemodynamics in Chronic Thromboembolic Pulmonary Hypertension

Alfredo Páez-Carpio, Llúria Cornellas, Ivan Vollmer, Blanca Domenech-Ximenos, Elena Serrano, Fernando M. Gómez, Joan A. Barberà, Isabel Blanco
article en

Abstract

This study presents a systematic application of a unified vascular obstruction scoring system across dual-energy CT, cone-beam CT, and digital subtraction angiography in patients with chronic thromboembolic pulmonary hypertension. The results demonstrate significant correlations with invasive hemodynamic parameters, with dual-energy CT and cone-beam CT providing higher reproducibility than angiography. These findings support the use of a standardized scoring framework to enable consistent multimodality assessment, improve reproducibility in structured multimodality imaging assessment, and facilitate cross-institutional comparisons in chronic thromboembolic pulmonary hypertension.

Academic Radiology
Bellvitge University Hospital (ES), Hospital Universitari i Politècnic La Fe (ES), Hospital Clínic de Barcelona (ES), Vall d'Hebron Hospital Universitari (ES), Fundació Clínic per a la Recerca Biomèdica (ES), Universitat de Barcelona (ES)
Openalex Percentile: Top 69%
Pulmonary Hypertension Research and Treatments
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