Expert recommendations for setting and adjusting airway pressure release ventilation based on clinical experience and basic science evidence

The panel developed a protocol for adjusting the four APRV settings based on expert experience and solid clinical and scientific evidence for patients with ALI and ARDS, or disorders of normal or increased elastance. Optimizing the lung-protective settings in APRV mode can improve patient outcomes.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-02-03
DOI
https://doi.org/10.3389/fmed.2026.1741129
Primary Topic
Respiratory Support and Mechanisms
Type
article
Field-Weighted Citation Impact
0.00
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article

Expert recommendations for setting and adjusting airway pressure release ventilation based on clinical experience and basic science evidence

Maria Madden, Jason H. T. Bates, Joseph Shiber, John S. Downs et al.
Frontiers in Medicine
Respiratory Support and Mechanisms
article

Expert recommendations for setting and adjusting airway pressure release ventilation based on clinical experience and basic science evidence

Maria Madden, Jason H. T. Bates, Joseph Shiber, John S. Downs, Joaquín Araos, Manjunath Markandaya, Nader M. Habashi, Toni Manougian, Hassan Al-Khalisy, Luigi Camporota, Penny L. Andrews, Pedro Leme Silva, Tero Varpula, Ledoux Aurelien, Gary F. Nieman, Luis Felipe da Fonseca Reis, Louise Rose, Josh Satalin
article en

Abstract

The panel developed a protocol for adjusting the four APRV settings based on expert experience and solid clinical and scientific evidence for patients with ALI and ARDS, or disorders of normal or increased elastance. Optimizing the lung-protective settings in APRV mode can improve patient outcomes.

Frontiers in MedicineVol. 13
University of Vermont (US), University of Maryland, Baltimore (US), University of Maryland Medical Center (US), Westchester Medical Center (US), University of Helsinki (FI), King's College London (GB), East Carolina University (US), Guy's and St Thomas' NHS Foundation Trust (GB), SUNY Upstate Medical University (US), Cornell University (US), University Center Augusto Motta (BR), University of Florida (US), Czech Academy of Sciences, Institute of Biophysics (CZ), Hôpital de Jolimont (BE), St. Mary's Hospital (US), Northeast Georgia Medical Center (US), Hospital Central da Polícia Militar (BR), New York State College of Veterinary Medicine (US), Florida College (US)
Good health and well-being
Openalex Percentile: Top 69%
Respiratory Support and Mechanisms
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Expert recommendations for setting and adjusting airway pressure release ventilation based on clinical experience and basic science evidence — Maria Madden, Jason H. T. Bates, et al. · Frontiers in Medicine (2026) | TGRS Research Map | TGRS