Efficacy and safety of adding a fourth oral antidiabetic drug versus metformin dose escalation in patients with type 2 diabetes inadequately controlled on triple oral combination therapy ( <scp>EFFORT</scp> ): A 24‐week, randomized, open‐label, multi
Oral quadruple therapy achieved greater glycaemic and metabolic improvement without compromising safety, compared with metformin uptitration, supporting its role as an intensification strategy.
Authors
- Ju-Young Moon (ORCID: https://orcid.org/0000-0003-3244-8371)
- So Ra Kim (ORCID: https://orcid.org/0000-0001-8786-2815)
- SIN GON KIM
- B W Lee
- Soo‐Kyung Kim (ORCID: https://orcid.org/0000-0002-2601-3438)
- Jae Myung Yu
- Jun Hwa Hong
- Hyuk‐Sang Kwon
- Jung Hwan Park
- Bong‐Soo Cha
Institutions
- Yonsei University (KR)
- Korea University (KR)
- Eulji University (KR)
- Hallym University Kangnam Sacred Heart Hospital (KR)
- The Catholic University of Korea Yeouido St. Mary's Hospital (KR)
- CHA University Bundang Medical Center (KR)
- Yeungnam University Medical Center (KR)
- Hanyang University (KR)
- Yeungnam University (KR)
Publication Details
- Journal
- Diabetes Obesity and Metabolism
- Published
- 2026-02-03
- DOI
- https://doi.org/10.1111/dom.70527
- Primary Topic
- Diabetes Treatment and Management
- Type
- article
- Field-Weighted Citation Impact
- 0.00