18FAl-NOTA-FAPI PET/CT Outperforms 18F-FDG PET/CT in Detecting Gastrointestinal Metastasis of Lobular Breast Carcinoma

A 57-year-old woman with a history of right breast cancer surgery 22 years prior presented with CT findings of gastric and intestinal wall thickening, accompanied by mild-to-moderate FDG uptake on 18F-FDG PET/CT. Pathological results showed lobular breast cancer metastasis. The lesions showed significantly higher uptake on 18FAl-NOTA-FAPI PET/CT, and an additional sternal metastasis was identified.

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Publication Details

Journal
Clinical Nuclear Medicine
Published
2025-10-15
DOI
https://doi.org/10.1097/rlu.0000000000006176
Primary Topic
Peptidase Inhibition and Analysis
Type
article
Field-Weighted Citation Impact
0.00
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article

18FAl-NOTA-FAPI PET/CT Outperforms 18F-FDG PET/CT in Detecting Gastrointestinal Metastasis of Lobular Breast Carcinoma

Annan Zhang, Yanpeng Ma, Meixin Zhao, Ming Zu et al.
Clinical Nuclear Medicine
Peptidase Inhibition and Analysis
article

18FAl-NOTA-FAPI PET/CT Outperforms 18F-FDG PET/CT in Detecting Gastrointestinal Metastasis of Lobular Breast Carcinoma

Annan Zhang, Yanpeng Ma, Meixin Zhao, Ming Zu, Shigang Ding
article en

Abstract

A 57-year-old woman with a history of right breast cancer surgery 22 years prior presented with CT findings of gastric and intestinal wall thickening, accompanied by mild-to-moderate FDG uptake on 18F-FDG PET/CT. Pathological results showed lobular breast cancer metastasis. The lesions showed significantly higher uptake on 18FAl-NOTA-FAPI PET/CT, and an additional sternal metastasis was identified.

Clinical Nuclear MedicineVol. 51(3)
Peking University (CN), University Gastroenterology (US), Peking University Third Hospital (CN)
Good health and well-being
Openalex Percentile: Top 28%
Peptidase Inhibition and Analysis
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