Discovery of an Artificial Intelligence Label Feedback Loop: How the Success of a Clinically Implemented Artificial Intelligence Algorithm Has Created an Unforeseen Challenge to Algorithm Retraining
The integration of AI into clinical practice can potentially influence reported test results, complicating the development and evaluation of future models. To mitigate AI label feedback loops, ongoing human annotation and careful validation set construction are essential. These strategies can ensure reliable performance assessment and support the safe evolution of clinical AI systems.
Authors
- R Carter
- Denise Rokke
- Éric Lantz (ORCID: https://orcid.org/0000-0002-1012-3309)
- Paul J. Jannetto (ORCID: https://orcid.org/0000-0002-5629-439X)
- Joshua A. Bornhorst (ORCID: https://orcid.org/0009-0003-9297-3271)
- Mikolaj A. Wieczorek (ORCID: https://orcid.org/0000-0002-7879-9727)
- Patrick L Day
Institutions
- Mayo Clinic in Arizona (US)
- Mayo Clinic in Florida (US)
Publication Details
- Journal
- Clinical Chemistry
- Published
- 2026-01-03
- DOI
- https://doi.org/10.1093/clinchem/hvag001
- Primary Topic
- Kidney Stones and Urolithiasis Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00