Discovery of an Artificial Intelligence Label Feedback Loop: How the Success of a Clinically Implemented Artificial Intelligence Algorithm Has Created an Unforeseen Challenge to Algorithm Retraining

The integration of AI into clinical practice can potentially influence reported test results, complicating the development and evaluation of future models. To mitigate AI label feedback loops, ongoing human annotation and careful validation set construction are essential. These strategies can ensure reliable performance assessment and support the safe evolution of clinical AI systems.

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Publication Details

Journal
Clinical Chemistry
Published
2026-01-03
DOI
https://doi.org/10.1093/clinchem/hvag001
Primary Topic
Kidney Stones and Urolithiasis Treatments
Type
article
Field-Weighted Citation Impact
0.00
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article

Discovery of an Artificial Intelligence Label Feedback Loop: How the Success of a Clinically Implemented Artificial Intelligence Algorithm Has Created an Unforeseen Challenge to Algorithm Retraining

R Carter, Denise Rokke, Éric Lantz, Paul J. Jannetto et al.
Clinical Chemistry
Kidney Stones and Urolithiasis Treatments
article

Discovery of an Artificial Intelligence Label Feedback Loop: How the Success of a Clinically Implemented Artificial Intelligence Algorithm Has Created an Unforeseen Challenge to Algorithm Retraining

R Carter, Denise Rokke, Éric Lantz, Paul J. Jannetto, Joshua A. Bornhorst, Mikolaj A. Wieczorek, Patrick L Day
article en

Abstract

The integration of AI into clinical practice can potentially influence reported test results, complicating the development and evaluation of future models. To mitigate AI label feedback loops, ongoing human annotation and careful validation set construction are essential. These strategies can ensure reliable performance assessment and support the safe evolution of clinical AI systems.

Clinical Chemistry
Mayo Clinic in Arizona (US), Mayo Clinic in Florida (US)
Openalex Percentile: Top 69%
Kidney Stones and Urolithiasis Treatments
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Discovery of an Artificial Intelligence Label Feedback Loop: How the Success of a Clinically Implemented Artificial Intelligence Algorithm Has Created an Unforeseen Challenge to Algorithm Retraining — R Carter, Denise Rokke, et al. · Clinical Chemistry (2026) | TGRS Research Map | TGRS