Long-term changes and risk factors for persistent cough and sputum in adult patients with asthma treated by Japanese specialists: The SARAS study (1997–2023)
Despite therapeutic advances and guideline-based specialist care, residual symptoms, especially cough and sputum, persisted in a significant proportion of Japanese adult patients with asthma. Comprehensive management strategies targeting comorbidities such as chronic rhinosinusitis and smoking are essential to achieve clinical remission and improve patient-centered outcomes.
Authors
- Hirotaka Nishikiori (ORCID: https://orcid.org/0000-0002-0573-9344)
- Eiki Kikuchi
- Chikako Kitamura
- Hirofumi Chiba (ORCID: https://orcid.org/0000-0002-7033-3084)
- Katsunori Shigehara (ORCID: https://orcid.org/0000-0001-9565-2068)
- Yoshitaka Sugawara
- Midori Hashimoto
- Yasuhito Honda
- T Yoshikawa
- Hiroshi Tanaka
- Takiko Aketa
- Chiaki Hamamatsu
- Toshiyuki Sumi
- Mitsuhide Ohmichi
- Eiji Ito
- Satsuki Miyajima
Institutions
- Sapporo Medical University (JP)
- NTT Medical Center (JP)
- Sapporo Science Center (JP)
- Sapporo Minami Hospital (JP)
- Minamiaoyama Eye Clinic (JP)
- Hakodate National Hospital (JP)
- Kishokai Medical Corporation (JP)
- Obihiro National Hospital (JP)
Publication Details
- Journal
- Allergology International
- Published
- 2026-02-01
- DOI
- https://doi.org/10.1016/j.alit.2025.12.007
- Primary Topic
- Respiratory and Cough-Related Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00