The Impact of Preoperative Inflammatory Activity in Patients with Ankylosing Spondylitis on Postoperative Joint Function: A Retrospective Cohort Study

These findings suggest that elevated preoperative inflammatory markers, particularly ESR, are not contraindications for THA in AS patients. Instead, they may indicate a greater capacity for postoperative functional recovery. The study supports a proactive surgical approach in appropriately selected AS patients, emphasizing the need for individualized assessment and consideration of systemic inflammation as a potential marker of postoperative improvement rather than a barrier to surgical intervention. These insights could refine surgical decision-making and optimize timing for THA in AS patients.

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Publication Details

Journal
Journal of Inflammation Research
Published
2026-02-01
DOI
https://doi.org/10.2147/jir.s576376
Primary Topic
Spondyloarthritis Studies and Treatments
Type
article
Field-Weighted Citation Impact
0.00

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article

The Impact of Preoperative Inflammatory Activity in Patients with Ankylosing Spondylitis on Postoperative Joint Function: A Retrospective Cohort Study

Xiaojian Ji, Siliang Man, Tao Bian, Liang Zhang et al.
Journal of Inflammation Research
Spondyloarthritis Studies and Treatments
article

The Impact of Preoperative Inflammatory Activity in Patients with Ankylosing Spondylitis on Postoperative Joint Function: A Retrospective Cohort Study

Xiaojian Ji, Siliang Man, Tao Bian, Liang Zhang, Shao-Yi Guo, Ying-Yue Ding, Hong-Chao Li
article en

Abstract

These findings suggest that elevated preoperative inflammatory markers, particularly ESR, are not contraindications for THA in AS patients. Instead, they may indicate a greater capacity for postoperative functional recovery. The study supports a proactive surgical approach in appropriately selected AS patients, emphasizing the need for individualized assessment and consideration of systemic inflammation as a potential marker of postoperative improvement rather than a barrier to surgical intervention. These insights could refine surgical decision-making and optimize timing for THA in AS patients.

Journal of Inflammation ResearchVol. Volume 19
Peking University (CN), Chinese PLA General Hospital (CN), Beijing Jishuitan Hospital (CN)
National Health Commission of the People's Republic of China
Peace, Justice and strong institutions
Openalex Percentile: Top 69%
Spondyloarthritis Studies and Treatments
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The Impact of Preoperative Inflammatory Activity in Patients with Ankylosing Spondylitis on Postoperative Joint Function: A Retrospective Cohort Study — Xiaojian Ji, Siliang Man, et al. · Journal of Inflammation Research (2026) | TGRS Research Map | TGRS