The Impact of Preoperative Inflammatory Activity in Patients with Ankylosing Spondylitis on Postoperative Joint Function: A Retrospective Cohort Study
These findings suggest that elevated preoperative inflammatory markers, particularly ESR, are not contraindications for THA in AS patients. Instead, they may indicate a greater capacity for postoperative functional recovery. The study supports a proactive surgical approach in appropriately selected AS patients, emphasizing the need for individualized assessment and consideration of systemic inflammation as a potential marker of postoperative improvement rather than a barrier to surgical intervention. These insights could refine surgical decision-making and optimize timing for THA in AS patients.
Authors
- Xiaojian Ji (ORCID: https://orcid.org/0000-0003-4753-191X)
- Siliang Man (ORCID: https://orcid.org/0000-0003-2109-1063)
- Tao Bian (ORCID: https://orcid.org/0000-0003-1600-077X)
- Liang Zhang
- Shao-Yi Guo
- Ying-Yue Ding
- Hong-Chao Li
Institutions
- Peking University (CN)
- Chinese PLA General Hospital (CN)
- Beijing Jishuitan Hospital (CN)
Publication Details
- Journal
- Journal of Inflammation Research
- Published
- 2026-02-01
- DOI
- https://doi.org/10.2147/jir.s576376
- Primary Topic
- Spondyloarthritis Studies and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Health Commission of the People's Republic of China