Association of serum methylglyoxal with endothelial dysfunction in patients with type 2 diabetes

MGO was significantly inversely associated with FMD and endothelial function in T2DM patients, and can be used as a biomarker to assess vascular endothelial health. Detection of serum MGO levels has clinical significance in the prevention of early diabetic vascular disease.

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Publication Details

Journal
Frontiers in Pharmacology
Published
2026-02-04
DOI
https://doi.org/10.3389/fphar.2026.1773149
Primary Topic
Advanced Glycation End Products research
Type
article
Field-Weighted Citation Impact
0.00
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article

Association of serum methylglyoxal with endothelial dysfunction in patients with type 2 diabetes

Jie Gao, Wenjun Sha, Shanshan Yu, Jun Lü et al.
Frontiers in Pharmacology
Advanced Glycation End Products research
article

Association of serum methylglyoxal with endothelial dysfunction in patients with type 2 diabetes

Jie Gao, Wenjun Sha, Shanshan Yu, Jun Lü, Tao Lei, Xinyan Jin, Zhao Liu, Yuanying Xu
article en

Abstract

MGO was significantly inversely associated with FMD and endothelial function in T2DM patients, and can be used as a biomarker to assess vascular endothelial health. Detection of serum MGO levels has clinical significance in the prevention of early diabetic vascular disease.

Frontiers in PharmacologyVol. 17
Shanghai University of Traditional Chinese Medicine (CN)
Good health and well-being
Openalex Percentile: Top 64%
Advanced Glycation End Products research
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