Overweight and obesity association with mortality in patients with heart failure and reduced or preserved ejection fraction-a cohort study
Excess weight was associated with an apparent survival benefit in patients with acute heart failure, particularly in patients with HFpEF. This advantage disappeared completely after adjustment for confounding factors including NT-proBNP. The obesity paradox can be completely explained by differences in demographics, co-morbidities, and severity of heart failure.
Authors
- David Carballo (ORCID: https://orcid.org/0000-0003-3212-1272)
- Nicolas Vuilleumier (ORCID: https://orcid.org/0000-0002-1122-438X)
- Nicolás Garin (ORCID: https://orcid.org/0000-0003-1269-1577)
- Jérôme Stirnemann
- Sebastian Carballo
- Jonathan Dash
- Jean-Luc Reny
Institutions
- University of Geneva (CH)
- University Hospital of Geneva (CH)
- Hôpital Riviera-Chablais (CH)
Publication Details
- Journal
- PLoS ONE
- Published
- 2026-02-03
- DOI
- https://doi.org/10.1371/journal.pone.0341606
- Primary Topic
- Cardiovascular Function and Risk Factors
- Type
- article
- Field-Weighted Citation Impact
- 0.00