Epidemiologic and Clinical Trends of Pediatric Human Rhinovirus Infections: A 2-year Comparative Analysis From a Single Center

Human rhinovirus cases nearly tripled across 2 seasons, yet clinical severity did not increase. Fever, cough and rhinorrhea declined, antibiotic use decreased and hospitalization remained stable. Coinfections became more frequent but did not affect outcomes. These observations suggest that rhinovirus circulation is expanding with a shift toward milder, community-managed illness.