Predictors of cognitive impairment in drug-resistant epilepsy: the role of interictal EEG abnormalities
Seizure burden emerged as the predominant predictor of CI with DRE, while interictal EEG abnormalities demonstrated a univariate correlation with cogntive status, this association was not independent in the adjusted analysis. EEG findings may still provide contextual or supportive clinical context, emphasize that a comprehensive approach integrating seizure management with cognitive assessments is warranted, rather than relying primarily on interictal EEG for cognitive risk stratification.
Authors
- Rakan Bokhari (ORCID: https://orcid.org/0000-0003-4157-1830)
- Motaz M. Fadul
- Maher Kurdi (ORCID: https://orcid.org/0000-0002-8979-3849)
- Mazen Basheikh (ORCID: https://orcid.org/0000-0001-8973-6118)
- Saleh S Baeesa
- Humaira Waseem
- Wareef Alzahrani
- Fawzi Babtain
- Mohammed Karami
- Amal Alkhotani
- Raed Gasemaltayeb
- Ahmed Bamaga
- Mohammed Alshurem
- Adnan Badahdah
- Ahmed Najjar
- Ahmad Albeshri
- Amber Hassan
- Yasser Alamri
Institutions
- INTI International University (MY)
- Alfaisal University (SA)
- King Abdulaziz University (SA)
- Umm al-Qura University (SA)
- Taibah University (SA)
- King Faisal Specialist Hospital & Research Centre (SA)
- King Abdulaziz Medical City (SA)
- University of Jeddah (SA)
- European School of Molecular Medicine (IT)
- CEINGE Biotecnologie Avanzate Franco Salvatore (Italy) (IT)
- King Abdulaziz Hospital (SA)
- National Guard Health Affairs (SA)
- Imam Abdulrahman Bin Faisal University (SA)
Publication Details
- Journal
- Acta Epileptologica
- Published
- 2026-02-04
- DOI
- https://doi.org/10.1186/s42494-026-00244-8
- Primary Topic
- Epilepsy research and treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00