Dietary intake of live microbes is inversely associated with fatigue and modified by serum folate among adults aged 40 years or more
Intake of microbe-rich foods and higher levels of circulating 5-methyltetrahydrofolate are both associated with lower levels of fatigue in midlife and older adults, and folate sufficiency appears to potentiate the fatigue-reducing benefits of live-microbe foods, supporting a nutrient-microbe pathway relevant to healthy aging.
Authors
- Amber S. Kleckner (ORCID: https://orcid.org/0000-0002-5088-1139)
- Alice S. Ryan (ORCID: https://orcid.org/0000-0003-3708-110X)
- Elizabeth A. Dennis
- Galya Bigman
- Yuanyuan Li
- John D. Sorkin
Institutions
- University of Maryland, Baltimore (US)
- Geriatric Research Education and Clinical Center (US)
- VA Maryland Health Care System (US)
- University of Maryland, College Park (US)
Publication Details
- Journal
- Maturitas
- Published
- 2026-02-03
- DOI
- https://doi.org/10.1016/j.maturitas.2026.108868
- Citations
- 1
- Primary Topic
- Folate and B Vitamins Research
- Type
- article
- Field-Weighted Citation Impact
- 46.80