αβT/CD19-depleted Allogeneic Stem Cell Transplantation in Adults with Inborn Errors of Immunity
In conclusion, ex vivo graft engineering using αβTCR/CD19 depletion was feasible in adults with IEI. Clinical outcomes are encouraging, but need to be confirmed in larger studies.
Authors
- Anna van Rhenen (ORCID: https://orcid.org/0000-0003-2276-8806)
- Iris Brinkman (ORCID: https://orcid.org/0000-0003-3772-5147)
- Janneke J. H. de Winter
- Helen L. Leavis (ORCID: https://orcid.org/0000-0001-8720-3684)
- Pleun Schonewille
- Laura G. M. Daenen
- Frances A. Verheij
- Moniek A. de Witte
- Birtan M. Ibrahimov
- Lotte E. van der Wagen
- Tim J. A. Hutten
- Marloes W. Heijstek
- Anke Janssen
- Anniek H. G. Stuut
- Jürgen Kuball
Institutions
- Utrecht University (NL)
- Heidelberg University (DE)
- University Hospital Heidelberg (DE)
- University Medical Center Utrecht (NL)
- Isala (NL)
Publication Details
- Journal
- Journal of Clinical Immunology
- Published
- 2026-02-03
- DOI
- https://doi.org/10.1007/s10875-025-01978-9
- Primary Topic
- Immunodeficiency and Autoimmune Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00