Fusobacterium nucleatum manipulates host autophagy to promote its intracellular survival and treatment resistance in nasopharyngeal carcinoma
Our findings elucidate a key mechanism by which F. nucleatum survives and promotes treatment resistance in NPC, providing a microbiological prognosis indicator for NPC patients.
Authors
- Sai-Wei Huang
- Ying-Qing Li (ORCID: https://orcid.org/0000-0001-8187-6714)
- Ye-lin Liang
- Jiewen Bai
- Shengsuo Ma (ORCID: https://orcid.org/0000-0002-0189-7150)
- Ying-Qi Lu (ORCID: https://orcid.org/0009-0001-0629-7015)
- Xi-Rong Tan
- Junyan Li (ORCID: https://orcid.org/0009-0008-1357-6590)
- Jia-Hao Dai
- Sha Gong
- Yu-Fei Duan
- Na Liu
- Cheng Xu
- Jing-Yun Wang
- Jun Ma
- Sen-Yu Feng
Institutions
- Sun Yat-sen University (CN)
- Sun Yat-sen University Cancer Center (CN)
Publication Details
- Journal
- Molecular Cancer
- Published
- 2026-02-03
- DOI
- https://doi.org/10.1186/s12943-026-02581-1
- Primary Topic
- Cancer Research and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Sun Yat-sen University
- Southern Medical University
- Sun Yat-sen University Cancer Center