Surgical complications of salpingo-oophorectomy in women undergoing risk-reducing surgery for hereditary breast and ovarian cancer - A retrospective cohort study

Risk reducing bilateral/unilateral salpingoophorectomy ± hysterectomy RESULTS: 246 women underwent surgery, and 15 (6.09%) experienced complications. 9 (60%) were Clavien Dindo grade I and 6 (40%) grade II. No grade III, IV, or V complications occurred. Grade I included minor pain or superficial infection not requiring antibiotic treatment, and grade II were all due to infections requiring treatment with antibiotics. No significant differences were found between women with and without complications with respect to age, BMI, previous abdominal surgery or smoking CONCLUSION: The incidence and severity of complications after risk reducing surgery were low. This evidence is valuable in counseling women with HBOC and offers reassurance about the safety of RRSO.

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Publication Details

Journal
Journal of Minimally Invasive Gynecology
Published
2026-02-01
DOI
https://doi.org/10.1016/j.jmig.2026.01.052
Primary Topic
BRCA gene mutations in cancer
Type
article
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article

Surgical complications of salpingo-oophorectomy in women undergoing risk-reducing surgery for hereditary breast and ovarian cancer - A retrospective cohort study

Klara Vinsand Naver, Julie Isabelle Plougmann Gislinge, Kresten Rubeck Petersen, Karin Anna Wallentin Wadt et al.
Journal of Minimally Invasive Gynecology
BRCA gene mutations in cancer
article

Surgical complications of salpingo-oophorectomy in women undergoing risk-reducing surgery for hereditary breast and ovarian cancer - A retrospective cohort study

Klara Vinsand Naver, Julie Isabelle Plougmann Gislinge, Kresten Rubeck Petersen, Karin Anna Wallentin Wadt, Anna Katrine Holst Lund, Pernille Ravn
article en

Abstract

Risk reducing bilateral/unilateral salpingoophorectomy ± hysterectomy RESULTS: 246 women underwent surgery, and 15 (6.09%) experienced complications. 9 (60%) were Clavien Dindo grade I and 6 (40%) grade II. No grade III, IV, or V complications occurred. Grade I included minor pain or superficial infection not requiring antibiotic treatment, and grade II were all due to infections requiring treatment with antibiotics. No significant differences were found between women with and without complications with respect to age, BMI, previous abdominal surgery or smoking CONCLUSION: The incidence and severity of complications after risk reducing surgery were low. This evidence is valuable in counseling women with HBOC and offers reassurance about the safety of RRSO.

Journal of Minimally Invasive Gynecology
Odense University Hospital (DK), Herlev Hospital (DK), Copenhagen University Hospital (DK)
Good health and well-being
Openalex Percentile: Top 65%
BRCA gene mutations in cancer
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Surgical complications of salpingo-oophorectomy in women undergoing risk-reducing surgery for hereditary breast and ovarian cancer - A retrospective cohort study — Klara Vinsand Naver, Julie Isabelle Plougmann Gislinge, et al. · Journal of Minimally Invasive Gynecology (2026) | TGRS Research Map | TGRS