Wharton's jelly mesenchymal stem cell-secretome enhances skin rejuvenation via ApoA4 and SERPINH1
The WJ-MSC secretome demonstrated consistent in-vitro pro-regenerative, anti-inflammatory, and antioxidant activities, with ApoA4 and SERPINH1 as candidate mediators. Human findings are preliminary/exploratory and suggest potential short-term benefits that require confirmation in adequately powered, controlled trials.
Authors
- Chi Young Bang (ORCID: https://orcid.org/0000-0001-8745-6489)
- Jong Ik Hwang
- Na Eun Lee (ORCID: https://orcid.org/0000-0002-3791-3933)
- Oh Young Bang
- Eun Hee Kim
Institutions
- Kangwon National University (KR)
- Samsung Medical Center (KR)
- Seoul Medical Center (KR)
- Bio-Medical Science (South Korea) (KR)
- Sungkyunkwan University (KR)
Publication Details
- Journal
- Regenerative Therapy
- Published
- 2026-02-04
- DOI
- https://doi.org/10.1016/j.reth.2026.101071
- Primary Topic
- Mesenchymal stem cell research
- Type
- article
- Field-Weighted Citation Impact
- 0.00