Efficacy, effectiveness, and safety of rho-kinase inhibitors in uveitic glaucoma and ocular hypertension secondary to uveitis: a systematic review and meta-analysis
ROCK inhibitors demonstrate significant and sustained IOP-lowering effects in UG and OHT-SU with a favorable safety profile. Their additive effect with conventional treatments and potential benefits in surgical outcomes highlight their role as promising therapeutic agents. Further clinical trials are needed to compare different ROCK inhibitors and assess their long-term safety and effectiveness in different populations.
Authors
- Germán Mejía‐Salgado (ORCID: https://orcid.org/0000-0002-1241-0715)
- Laura Zárate-Pinzón (ORCID: https://orcid.org/0000-0003-0295-4986)
- Juanita Cardona-López (ORCID: https://orcid.org/0009-0004-3888-3870)
- Fernando Gómez-Goyeneche
- Blanca Aguilar-Barrera
- David Santiago Escobar-Sánchez
- Alejandra de-la-Torre
- Alejandra Reyes-Troncoso
- Fábian Andrés Guauque
- Ana María Camacho-Romero
- Valentina Suarez-Carreño
- Sofía Gómez-Vargas
- Stefania García-García
- Julian Beltrán-Briceño
- Santiago David Acosta-Alzamora
Institutions
- Universidad Autónoma de Bucaramanga (CO)
- Universidad del Rosario (CO)
Publication Details
- Journal
- Graefe s Archive for Clinical and Experimental Ophthalmology
- Published
- 2026-02-03
- DOI
- https://doi.org/10.1007/s00417-025-07111-1
- Primary Topic
- Ocular Diseases and Behçet’s Syndrome
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Universidad del Rosario