A Dual-Stimuli Responsive Nanoplatform via Atomic Layer Deposition of Gold on CoFe2O4 for Thermally Gated Doxorubicin Delivery in Colorectal Cancer
This ALD-engineered CFO/Au-2/PAA/DOX/TD nanoplatform integrates magnetic and photothermal heating with thermally gated, dual-stimuli-responsive drug release, enabling precise spatiotemporal control of DOX delivery. The results suggest strong potential for combined and localized colorectal cancer therapy with reduced systemic toxicity.
Authors
- Lei Liang (ORCID: https://orcid.org/0000-0003-1028-0782)
- Huizhen Li (ORCID: https://orcid.org/0009-0003-8013-7655)
- Lang Liu
- Tianlin Wang
- Yutian Zhang
- Hong Wang
- Ziyi Qu
Institutions
- Guangzhou University of Chinese Medicine (CN)
- Tianjin University of Traditional Chinese Medicine (CN)
- National University of Defense Technology (CN)
Publication Details
- Journal
- International Journal of Nanomedicine
- Published
- 2026-02-01
- DOI
- https://doi.org/10.2147/ijn.s563711
- Primary Topic
- Nanoplatforms for cancer theranostics
- Type
- article
- Field-Weighted Citation Impact
- 0.00