Identification and Validation of a Novel Theranostic Target in Triple Negative Breast Cancer with Transcriptomics and Protein Analyses
In conclusion, this study suggests LY6E as a potential target for the selective imaging and therapy of TNBC, identified by transcriptomics analysis and cell line experiments. It lays the groundwork to augment clinical impact of future preclinical studies for the development of diagnostic and treatment approaches for TNBC.
Authors
- G.S. Kim
- Hyunjong Lee (ORCID: https://orcid.org/0000-0001-5680-1382)
- Mina Kim (ORCID: https://orcid.org/0000-0002-7832-9880)
- Kyung-Ho Jung
- Kyung-Han Lee
- Jung Yee Kim Jung Yee Kim
Institutions
- Samsung Medical Center (KR)
- Sungkyunkwan University (KR)
Publication Details
- Journal
- Breast Cancer Targets and Therapy
- Published
- 2026-02-01
- DOI
- https://doi.org/10.2147/bctt.s568001
- Primary Topic
- Cancer Immunotherapy and Biomarkers
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Research Foundation
- National Research Foundation of Korea
- Ministry of Science and ICT, South Korea