Evaluation of neutrophil activation in autoimmune kidney diseases using blood heparin-binding protein: a pilot study

Blood HBP is a valuable and eGFR-independent marker of neutrophil activation. This study preliminarily reveals that neutrophil activation is widespread in various autoimmune kidney diseases and may be involved in the pathogenesis of these diseases.

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Publication Details

Journal
Frontiers in Medicine
Published
2026-02-04
DOI
https://doi.org/10.3389/fmed.2026.1727663
Primary Topic
Neutrophil, Myeloperoxidase and Oxidative Mechanisms
Type
article
Field-Weighted Citation Impact
0.00

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article

Evaluation of neutrophil activation in autoimmune kidney diseases using blood heparin-binding protein: a pilot study

Huichao Chen, Heng Zhang, Zirui Liu, Zhen-Jun Zhao et al.
Frontiers in Medicine
Neutrophil, Myeloperoxidase and Oxidative Mechanisms
article

Evaluation of neutrophil activation in autoimmune kidney diseases using blood heparin-binding protein: a pilot study

Huichao Chen, Heng Zhang, Zirui Liu, Zhen-Jun Zhao, Ming-Xuan Gao, Jun-Ya Jia, Ying Gao, Chen-xi Cai, Xin-yue Shi, Peng-cheng Xu
article en

Abstract

Blood HBP is a valuable and eGFR-independent marker of neutrophil activation. This study preliminarily reveals that neutrophil activation is widespread in various autoimmune kidney diseases and may be involved in the pathogenesis of these diseases.

Frontiers in MedicineVol. 13
Tianjin Medical University General Hospital (CN), Mongolian National University (MN), Tianjin Medical University (CN)
Tianjin Medical University
Good health and well-being
Openalex Percentile: Top 68%
Neutrophil, Myeloperoxidase and Oxidative Mechanisms
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