Relationship between locus coeruleus and slow‐wave sleep in aging and Alzheimer's disease

LC integrity, sex, and PVS burden show associations with SWS alterations in aging and AD, supporting restorative sleep as a potential therapeutic target.

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Publication Details

Journal
Alzheimer s & Dementia
Published
2026-02-01
DOI
https://doi.org/10.1002/alz.71183
Primary Topic
Sleep and Wakefulness Research
Type
article
Field-Weighted Citation Impact
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article

Relationship between locus coeruleus and slow‐wave sleep in aging and Alzheimer's disease

Agnès Pérez‐Millan, Aurora Arqueros, Adrià Tort‐Merino, M. Morales Ruiz et al.
Alzheimer s & Dementia
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Relationship between locus coeruleus and slow‐wave sleep in aging and Alzheimer's disease

Agnès Pérez‐Millan, Aurora Arqueros, Adrià Tort‐Merino, M. Morales Ruiz, Salvatore Rudilosso, Guadalupe Fernández‐Villullas, Marta Peña‐González, Beatriz Muries Bosch, Mircea Balasa, Oriol Grau‐Rivera, Núria Tort‐Colet, Emma Muñoz‐Moreno, Gerard Piñol‐Ripoll, G. Mayà, Raquel Sánchez‐Valle, Alex Iranzo, Albert Lladó, Carles Gaig, Isabel Martín‐Sobrino, Neus Falgàs
article en

Abstract

LC integrity, sex, and PVS burden show associations with SWS alterations in aging and AD, supporting restorative sleep as a potential therapeutic target.

Alzheimer s & DementiaVol. 22(2)
Universitat Oberta de Catalunya (ES), Universidade de São Paulo (BR), Jacksonville College (US), Biomedical Research Networking Center on Neurodegenerative Diseases (ES), University Memory and Aging Center (US), Pasqual Maragall Foundation (ES), Hospital Clínic de Barcelona (ES), Centro de Investigación Biomédica en Red de Enfermedades Hepáticas y Digestivas (ES), Mayo Clinic in Florida (US), Centro de Investigación Biomédica en Red de Fragilidad y Envejecimiento Saludable (ES), Fundació Clínic per a la Recerca Biomèdica (ES), Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES), Universitat de Barcelona (ES)
Openalex Percentile: Top 69%
Sleep and Wakefulness Research
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